His work in the manipulation of cells laid the foundation for stem cell biology and regenerative medicine and led to the ...

Researchers at the First Affiliated Hospital of the University of Science and Technology of China claim that an in vivo CD8 T ...

Living with an autoimmune disease often means navigating a lifelong, complex condition. A recent study estimates that ...

Johns Hopkins scientists discovered a way to convert “immune-cold” tumors into “immune-hot” ones by activating key immune pathways. In studies using mouse models of breast, pancreatic, and muscle ...

Immusoft of CA, a clinical stage, engineered B cell company, today announced a historic achievement: the safe and well-tolerated re-dosing of a patient with a gene modified therapeutic product ...

Scientists at City of Hope have uncovered a gene called SMOC1 that plays a surprising role in the development of type 2 ...

Hodgkin lymphoma and other malignancies that express the CD30 protein have been the scourge of oncologists for decades. For ...

CD19-targeting UB-VV11 became the first in vivo CAR-T cell therapy to be cleared for human testing by the FDA last year, and ...

Recent research indicates that the spatial architecture of membrane proteins is crucial for regulating T-cell signaling and activation. 3-5 In the context of CAR T cells, the nanoscale localization ...

In vivo CD19 CAR T-cell therapy showed promising results in a feasibility study of five patients with refractory systemic ...

In this video, Tycel Phillips, MD, discusses initial results of a phase 1b clinical trial focused on treating diffuse large B ...

Abdominal pain is a hallmark of many digestive disorders, including inflammatory bowel disease and irritable bowel syndrome.