Dane -- who shot to fame amid six seasons on the hit ABC drama "Grey's Anatomy," where he played Dr. Mark Sloan, affectionately known as "McSteamy" -- said his symptoms began over one year ago, when he began to experience weakness in his right hand.

Eric Dane is sharing the first heartbreaking details about the challenges stemming from his ALS battle. The "Grey's Anatomy" star, 52, sat down for his first TV interview since going public with the illness,

Eric Dane is not backing down from his fight against ALS. The 52-year-old sat down with ABC News' Diane Sawyer in an interview for Good Morning America, where he revealed his first symptoms of the debilitating disease and how he plans to slow the effects.