Tumors are not a comfortable place to live: oxygen deficiency, nutrient scarcity, and the accumulation of sometimes harmful metabolic products constantly stress cancer cells.

Elevated calcium levels in the blood—a complication of kidney cancers known as hypercalcemia—may be successfully treated with a class of medications called HIF-2α inhibitors developed by UT ...

Freezer burn is bad enough when it comes to ice cream, but the tiny, jagged ice crystals pose problems for much bigger issues than ruining your dessert. If frozen for too long, ice particles begin to ...

Explore the latest advancements in liquid biopsy for oncology, examining current trends and insights that could shape future cancer diagnostics. Read more.

Johns Hopkins researchers found a way to build lasting tumor-fighting immunity and prevent cancer recurrence by turning “immune-cold” tumors into “immune-hot” tumors. This ...

Johns Hopkins scientists discovered a way to convert “immune-cold” tumors into “immune-hot” ones by activating key immune pathways. In studies using mouse models of breast, pancreatic, and muscle ...

From bispecific engineering to clinically relevant data sourcing, evolving antibody technologies advance oncology therapeutics.

When cancer cells are physically squeezed, they mount an instant, high-energy defense by rushing mitochondria to the cell nucleus, unleashing a surge of ATP that fuels DNA repair and survival. This ...

Zeaxanthin, an eye health nutrient, boosted tumor-fighting T cells and slowed cancer growth in mice. Human trials are still needed.

RNA-protein interactions regulate many essential processes in cells, from turning genes on and off to responding to stress. But until now, scientists could only capture small subsets of these ...

Several medical conditions can mimic prostate cancer, causing many of the same symptoms, including painful ejaculation and blood in the urine. Some of these conditions can also cause elevated prostate ...

Zeaxanthin, best known for eye health, has been found to boost the tumor-killing power of T cells. Researchers showed it strengthens T-cell receptors, enhances immune signaling, and improves the ...