The potential market for the drugs is massive — more than 40 percent of adults in the U.S. are obese — and has seen explosive growth. The number of Americans taking GLP-1s for weight loss rose more ...

BUFFALO, N.Y. — With more wintry weather on the way, local highway departments will now have more road salt to make the situation safer for drivers. 2 on Your Side spoke with a top Erie County ...

The rest stop is the 25th to reopen as part of the New York State Thruway Authority's rehab of all 27 locations.

In 1735, fraudulent document conceived by William Penn’s son Thomas would swindle the Lenape tribe out of 1,200 square miles ...

With its close proximity to Mount Rushmore, Custer State Park, and the breathtaking Badlands, Rapid City is an ideal base for ...

The fate of a former Macy's location that closed in Pittsburgh a decade ago could inform what happens with the Wanamaker ...

A fast-casual restaurant chain is expanding its footprint in four different states, including its home state of Pennsylvania with a new Allentown area location.

As the nation prepares to celebrate its 250th birthday in 2026, spend 2025 visiting these 12 Revolutionary War sites in New ...

American Airlines Flight 5342 and a U.S. Army Black Hawk collided in Washington, D.C. Authorities believe all 67 on board ...

Bulletin: ...WINTER WEATHER ADVISORY REMAINS IN EFFECT FROM 3 PM THIS AFTERNOON TO 6 AM EST SUNDAY... * WHAT...Mixed ...