Scientists discovered a key molecular switch to keep neurons healthy by controlling the disassembly and assembly of their ...

Specific glycans attached to the GnT-IVa and GnT-IVb can bind to the enzyme’s ligand-binding site, interfering with recognition and binding to the glycosylation proteins’ normal glycoprotein ...

Iridoids are a widespread and evolutionarily ancient class of plant secondary metabolites belonging to the terpenes. They ...

Scientists have found that the activity of proprotein covertases, the enzymes that turn-on proteins, is regulated by the location of the enzyme inside the cell. The study uses a novel biosensor, CLIP, ...

Researchers have long believed that neurons rely on glucose nearly entirely for fuel. The brain’s enormous energy ...

The brain has the ability to modify the contacts between neurons. Among other things, that is how it prevents brain activity from getting out of control. Researchers have now identified a mechanism ...

Levels of the enzyme HO-1, which protects against toxicity, are elevated in sickle cell disease patients, especially children ...