A new study by University of Bath scientists has highlighted two new potential families of drug molecules that could open the ...

The first low-resolution structure, aided by docking with AlphaFold2, the artificial intelligence protein structure prediction system, showed the domain that spans the inner membrane of M.

More information: Jennifer C. Earp et al, Structural basis of siderophore export and drug efflux by Mycobacterium tuberculosis, Nature Communications (2025). DOI: 10.1038/s41467-025-56888-6 ...

The protein MmpL5 is an efflux transporter, a critical pump that helps the pathogen M. tuberculosis grow by scavenging essential iron. Unfortunately, overexpressed MmpL5 can also pump out ...

Arun Kumar Gupta Environmental pollution today stands as one of the most significant challenges faced by humanity. Its ...

The Institute has a strong pedigree in understanding the fundamental mechanisms that underpin the success of vaccination and in the development of novel vaccines and their mode of action.

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You’d be excused for being suspicious of these concoctions. Poured into clear-glass one-gallon jars of unregulated ...

New drugs that target "zombie" tuberculosis (TB) cells are now a step closer, thanks to a new study led by the University of ...

He isolated rod-shaped bacteria from sputum coughed up by people with TB. Koch’s discovery of M. tuberculosis soon persuaded the medical world that the disease was infectious rather than hereditary.