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Adjunctive middle meningeal artery embolization may reduce the ...
Dec 12, 2024 · 1. In this randomized controlled trial, middle meningeal artery embolization plus surgical evacuation was associated with a lower risk of hematoma recurrence or progression …
Ponsegromab for the Treatment of Cancer Cachexia
Sep 23, 2024 · 1. Ponsegromab at increasing doses resulted in a mean increase in body weight compared to placebo; 1.22 kg (2.21%) in the 100-mg group, 1.92 kg (2.99%) in the 200-mg …
Amivantumab plus lazertinib improves survival in EGFR-mutated …
Nov 27, 2024 · 1. In this randomized trial, amivantamab-lazertinib led to significantly longer progression-free survival than osimertinib therapy for mutated advanced non-small-cell lung …
Radiotherapy and abiraterone improve survival in low-volume …
Dec 18, 2024 · 1. Progression-free survival improved significantly in patients with low-volume disease who received abiraterone and radiotherapy. 2. The addition of radiotherapy did not …
Belzutifan versus Everolimus for Advanced Renal-Cell Carcinoma
Sep 9, 2024 · In-Depth [randomized controlled trial]: This phase 3, multicenter, open-label trial enrolled adults with stage IV clear-cell renal-cell carcinoma who had disease progression after …
Fosrolapitant/Palonosetron in Chemotherapy-Induced Nausea and …
Dec 9, 2024 · 1. The complete response rate at the overall phase in cycle 1 was 77.7% vs 78.2% with treatment vs control groups (significant for noninferiority). 2. Treatment-related adverse …
RAMOSE Phase II trial finds promising results for osimertinib and ...
Dec 10, 2024 · 1. Treatment of patients with tyrosine kinase inhibitor (TKI)-naïve epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) with osimertinib …
Influenza vaccination may reduce secondary infection spread …
Dec 1, 2024 · 1. Influenza vaccination was associated with a reduced risk of secondary influenza infections among household contacts, with an estimated effectiveness of 21%. Evidence …
Imlunestrant with or without Abemaciclib in Advanced Breast Cancer
Dec 16, 2024 · 1. Median progression-free survival was 9.4 months in the imlunestrant–abemaciclib group vs 5.5 months in the imlunestrant group with HR 0.57 …