Epilepsy (Generalized Tonic–Clonic Seizures) – Drug of Choice Tab. Sodium Valproate 500 mg PO BD Dose: Start 10–15 mg/kg/day, increase to 20–30 mg/kg/day in divided doses. Uses First-line drug for generalized tonic–clonic seizures. Also useful in myoclonic and absence seizures. Mechanism of Action ↑ GABA levels → enhances inhibitory transmission. Blocks voltage-gated sodium channels → stabilizes neuronal membranes. Blocks T-type calcium channels → suppresses abnormal discharges. Prescription Tab
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8.5K views · 16 reactions | Valproate is an epilepsy drug that can cause what is called Valproate Syndrome in children born to women using the drug. Sky’s Jason Farrell explains.  Link in bio to read more #Valproate #epilepsy #ValproateSyndrome | Sky News | Facebook
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On our last visit to Parliament in December, we met with and fully briefed Maria Goldman MP. We thank her for today raising Valproate again in the house and her invaluable support for those harmed by Sodium Valproate. | FACSA - Fetal Anti Convulsant Syndrome Association
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